The quality and performance of education systems, especially the performance of teachers, influence the quality and effectiveness of educational systems especially in schools of the developing world that provide education in the public sector. Government schools within the Punjab province of Pakistan are still struggling with the factors of poor motivation of teachers, poor working conditions, and weak institutional support. Under the quantitative research design, data were gathered using 300 teachers who worked in government schools of Multan district using a structured questionnaire. The proposed relationships were tested by use of Pearson correlation and multiple regression analysis. The results indicate that job satisfaction plays a great and non-negative role in the teacher performance, and positive work environment also plays a great role in the enhancement of the instructional performance. The findings reveal that intrinsic and extrinsic motivational elements should be considered in order to improve the performance of teachers.